The JAK-STAT pathway mediates both inflammatory and normal physiological functions.^1-3

Key cytokines of the JAK-STAT pathway^2,*

GM-CSF, granulocyte-macrophage colony-stimulating factor; HCP, healthcare provider; IFN, interferon; IL, interleukin; JAK, Janus kinase; NK, natural killer; RA, rheumatoid arthritis; STAT, signal transducer and activator of transcription.

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