Ulcerative Colitis

Cytokines and the JAK-STAT Pathway in UC*


Find out more about the unique role of JAKs in cytokine
signalling, with detailed content and teaching materials on UC pathogenesis.



Learn about UC
inflammatory pathways.

JAK-STAT Pathway

Discover the JAK-STAT pathway in UC.

JAK Pairings

Find out more about JAK pairings in UC.

JAK-STAT Function 

Find out why the JAK-STAT pathway is of particular therapeutic interest in UC.

JAK, Janus kinase; STAT, signal transducer and activator of transcription; UC, ulcerative colitis.

* Note that some of the information contained in this section pertains to preclinical studies in mice.